Recombinant TFEB anticorps (C-Term)

N° du produit ABIN7795623

L’anticorps Lapin Monoclonal anti-TFEB a été validé pour WB, FACS et IP. Il convient pour détecter TFEB dans des échantillons de Humain et Souris.

Aperçu rapide pour Recombinant TFEB anticorps (C-Term) (ABIN7795623)

Antigène: TFEB (Transcription Factor EB (TFEB))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TFEB est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: BLR070G

Détail du produit anti-TFEB anticorps

Épitope: C-Term

Fonction: Rabbit anti-TFEB Recombinant Monoclonal Antibody [BLR070G] - BSA-Free

Purification: Purified

Immunogène: Between 426 and C-terminus

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2 - 8 °C

Date de péremption: 12 months

Détails sur TFEB

Antigène: TFEB (Transcription Factor EB (TFEB))

Autre désignation: TFEB

Sujet: Transcription factor EB (TFEB) specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, TFEB activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. TFEB specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression, thus, TFEB plays a central role in expression of lysosomal genes. TFEB also specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P19484].

ID gène: 7942

UniProt: P19484